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Peptic ulcer disease is when the inner part of the stomach's gastric mucosa (lining of the stomach), the first part of the small intestine, or sometimes the lower esophagus, gets damaged. An ulcer in the stomach is called a gastric ulcer, while one in the first part of the intestines is a duodenal ulcer. [1]
The main clinical manifestations of ZES are peptic ulcers and diarrhea. [12] The initial diagnostic test for ZES is a fasting serum gastrin level when antisecretory medications are stopped. If the gastrin level is high, the acidity of the stomach is measured using pH or gastric analysis.
Peptic ulcer disease; Infections, such as tuberculosis; and infiltrative diseases, such as amyloidosis. A rare cause of gastric outlet obstruction is blockage with a gallstone, also termed "Bouveret syndrome" or "Bouveret's syndrome". In children, congenital pyloric stenosis / congenital hypertrophic pyloric stenosis may be a cause.
Infobox for medical conditions Template parameters [Edit template data] This template prefers block formatting of parameters. Parameter Description Type Status name name Name of disease or medical condition (should be the same as the title of the article) Example Posttraumatic stress disorder String required synonym synonym synonyms Common terms for the illness or condition. Example Upper ...
This is a timeline of the events relating to the discovery that peptic ulcer disease and some cancers are caused by H. pylori. In 2005, Barry Marshall and Robin Warren were awarded the Nobel Prize in Physiology or Medicine for their discovery that peptic ulcer disease (PUD) was primarily caused by Helicobacter pylori , a bacterium with affinity ...
Several anti-ulcer dosing regimens that combine antibiotics and proton pump inhibitors (PPI) to treat helicobacter pylori (H. pylori) induced peptic ulcer disease (PUD). The role of antibiotic in the therapies is to eradicate H. pylori, while the action of PPI is to reduce gastric acid secretion.
The clinical examination and patient history should look for alarm symptoms. Alarm symptoms include dysphagia , especially if progressive, or odynophagia , overt gastrointestinal bleeding , such as melena or hematemesis , persistent vomiting , unintentional weight loss , family history of gastric or esophageal cancer , palpable abdominal or ...
Oral symptoms can be similar to lesions occurring elsewhere in the digestive tract, with a pattern of swelling, inflammation, ulcers, and fissures. If these signs are present, then patients are more likely to also have anal and esophageal lesions and experience other extra-intestinal disease manifestations. [2]