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Vitamin B 12 deficiency can be determined, but not always. [14] This means it measures forms of vitamin B 12 that are "active" and can be used by the body, as well as the "inactive" forms, which cannot. [151] Vitamin B 12 deficiency can be found within normal levels, so clinical symptoms should be taken into account when a diagnosis is made. [2]
Patients present with weakness of the legs, arms, and trunk, and tingling and numbness that progressively worsens. Vision changes and change of mental state may also be present. Bilateral spastic paresis may develop and pressure, vibration, and touch sense are diminished. A positive Babinski sign may be seen. [7]
Peripheral neuropathy may first be considered when an individual reports symptoms of numbness, tingling, and pain in feet. After ruling out a lesion in the central nervous system as a cause, a diagnosis may be made on the basis of symptoms, laboratory and additional testing, clinical history, and a detailed examination.
“A B12 deficiency can cause physical and neurological symptoms, and research is also growing to support that it can also cause psychological issues as well,” says Shapiro. The list of ...
According to Healthline, common causes linked to tingling in the fingers include: Diabetic neuropathy. Nutritional deficiency of vitamin B12, vitamin B6, vitamin E or vitamin B9 (folate). Carpal ...
"If they have a noted deficiency, I might put them on a higher dose—500 micrograms or 1000 micrograms—and see how they feel." ... Symptoms of low B12 levels can also mimic signs of dementia.
Pernicious anemia often presents slowly, and can cause harm insidiously and unnoticeably. Untreated, it can lead to neurological complications, and in serious cases, death. [19] The onset may be vague and slow and the condition can be confused with other conditions, and there may be few to many symptoms without anemia. [20]
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