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For dogs, a dose ranges from 2.75 - 5.5 mg/kg once a day. The duration of treatment is usually at least five days, longer if there is a concurrent fungal or yeast infection. [ 4 ] Maximum duration of treatment is 30 days.
Side effects from intra-articular administration can include joint pain, swelling, lameness, and, rarely, infection of the joint. Intramuscular injection can cause dose-dependent inflammation and bleeding, since PSGAG is an analogue of the anticoagulant heparin. [4] In dogs, this may manifest as bleeding from the nose or as bloody stools. [7]
Butorphanol is available as the tartrate salt in injectable, tablet, and intranasal spray formulations. The tablet form is only used in dogs, cats and horses due to low bioavailability in humans. It was patented in 1971 and approved for medical use in 1979.
Acrylamide (or acrylic amide) is an organic compound with the chemical formula CH 2 =CHC(O)NH 2. It is a white odorless solid, soluble in water and several organic solvents. From the chemistry perspective, acrylamide is a vinyl-substituted primary amide (CONH 2 ).
Polyacrylamide is of low toxicity but its precursor acrylamide is a neurotoxin and carcinogen. [1] Thus, concerns naturally center on the possibility that polyacrylamide is contaminated with acrylamide. [12] [13] Considerable effort is made to scavenge traces of acrylamide from the polymer intended for use near food. [1]
Brain death is observed first. Breathing generally stops within seconds. However, euthanasia may be delayed in dogs that have deficient cardiac and circulatory function. [2] The pentobarbital component produces anaesthesia and rapid unconsciousness. A lethal dose causes loss of medullary respiration and vasomotor function.
Pradofloxacin, sold under the brand name Veraflox among others, is a third-generation enhanced spectrum veterinary antibiotic of the fluoroquinolone class. [5] It was developed by Elanco Animal Health GmbH and received approval from the European Commission in April 2011, for prescription-only use in veterinary medicine for the treatment of bacterial infections in dogs and cats.
Potassium bromide (K Br) is a salt, widely used as an anticonvulsant and a sedative in the late 19th and early 20th centuries, with over-the-counter use extending to 1975 in the US. Its action is due to the bromide ion (sodium bromide is equally effective). Potassium bromide is used as a veterinary drug, in antiepileptic medication for dogs.
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