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Enterotoxins have a particularly marked effect upon the gastrointestinal tract, causing traveler's diarrhea and food poisoning. The action of enterotoxins leads to increased chloride ion permeability of the apical membrane of intestinal mucosal cells.
Heat-stable enterotoxins (STs) are secretory peptides produced by some bacterial strains, such as enterotoxigenic Escherichia coli [2] which are in general toxic to animals. These peptides keep their 3D structure and remain active at temperatures as high as 100 °C.
Bacterial growth results in production of enterotoxins, one of which is highly resistant to heat and acids (pH levels between 2 and 11); [45] ingestion leads to two types of illness: diarrheal and emetic (vomiting) syndrome. [46] The enterotoxins produced by B. cereus have beta-hemolytic activity. [14]
Studies have shown that esophageal cancer can be related back to corn grain that contains fumonisins. [38] Other effects from fumonisins are birth defects of the brain, spine, and spinal cord. [38] In animals, problems with the pulmonary edema and hydrothorax swines have been proven to have association with fumonisins. [38]
Koch's postulation was proven correct by Indian microbiologist Sambhu Nath De, who in 1951 studied and documented the effects of injecting rabbits with heat-killed cholera bacteria. [5] He concluded from this experiment that an endotoxin liberated upon disintegration of the bacteria was the cause of the symptoms of cholera. [ 5 ]
Oxygen is required in order to produce TSST-1, [7] in addition to the presence of animal protein, low levels of glucose, and temperatures between 37–40 °C (99–104 °F). [1] Production is optimal at pH's close to neutral and when magnesium levels are low, [ 8 ] and is further amplified by high concentrations of S. aureus , which indicates ...
Campylobacter jejuni is a species of pathogenic bacteria that is commonly associated with poultry, and is also often found in animal feces.This species of microbe is one of the most common causes of food poisoning in Europe and in the US, with the vast majority of cases occurring as isolated events rather than mass outbreaks.
[2] [failed verification] The ones that do are collectively known as enterohemorrhagic E. coli (EHEC) and are major causes of foodborne illness. When infecting the large intestine of humans, they often cause gastroenteritis , enterocolitis , and bloody diarrhea (hence the name "enterohemorrhagic") and sometimes cause a severe complication ...