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  2. Megavitamin-B6 syndrome - Wikipedia

    en.wikipedia.org/wiki/Megavitamin-B6_syndrome

    Megavitamin-B 6 syndrome has been reported in doses as low as 24 mg/day. [34] Symptoms may also be dependent on the form of vitamin B 6 taken in supplements. [27] [35] It has been proposed that vitamin B 6 in supplements should be in pyridoxal or pyridoxal phosphate form rather than pyridoxine as these are thought to reduce the likelihood of ...

  3. Toxic and nutritional optic neuropathy - Wikipedia

    en.wikipedia.org/wiki/Toxic_and_nutritional...

    Nutritional optic neuropathy is treated with improved nutrition. A well-balanced diet with plenty of protein and green leafy vegetables, vitamin supplementation (thiamine, vitamin B 12, folic acid, multivitamins), and reduction of smoking and/or drinking are the mainstay of treatment. Again, prognosis is variable and dependent upon the affected ...

  4. Vitamin B6 - Wikipedia

    en.wikipedia.org/wiki/Vitamin_B6

    A common side effect is numbness in the hands and feet, also known as peripheral neuropathy. [18] Co-treatment with vitamin B 6 alleviates the numbness. [19] Overconsumption of seeds from Ginkgo biloba can deplete vitamin B 6, because the ginkgotoxin is an anti-vitamin (vitamin antagonist). Symptoms include vomiting and generalized convulsions.

  5. Sensory neuronopathy - Wikipedia

    en.wikipedia.org/wiki/Sensory_neuronopathy

    Vitamin B6 is thought to lead to neuropathy due to its cytoskeletal and microtubule toxicity leading to nerve cell loss with prolonged overdosing. [ 2 ] Possible infectious causes of sensory neuronopathy include HIV (in which lymphocyte infiltrates have been observed in the dorsal root ganglion), Human T-lymphotropic virus 1 , Epstein-Barr ...

  6. Hypervitaminosis - Wikipedia

    en.wikipedia.org/wiki/Hypervitaminosis

    Hypervitaminosis is a condition of abnormally high storage levels of vitamins, which can lead to various symptoms as over excitement, irritability, or even toxicity. Specific medical names of the different conditions are derived from the given vitamin involved: an excess of vitamin A, for example, is called hypervitaminosis A.

  7. Vitamin B12 deficiency - Wikipedia

    en.wikipedia.org/wiki/Vitamin_B12_deficiency

    Risk of toxicity due to vitamin B 12 is low. [2] Vitamin B 12 deficiency in the US and the UK is estimated to occur in about 6 percent of those under the age of 60, and 20 percent of those over the age of 60. [4] In Latin America, about 40 percent are estimated to be affected, and this may be as high as 80 percent in parts of Africa and Asia. [1]

  8. Sexual anhedonia - Wikipedia

    en.wikipedia.org/wiki/Sexual_anhedonia

    A sudden-onset sexual anhedonia can also be a symptom of sensory neuropathy, which is most commonly the result of pyridoxine toxicity [4] (e.g., from large doses of vitamin B6 supplements). In this case, the sexual dysfunction promptly resolves spontaneously once the B6 supplementation is stopped. [citation needed]

  9. Isoniazid - Wikipedia

    en.wikipedia.org/wiki/Isoniazid

    Vitamin B6 is used to prevent isoniazid-induced B6 deficiency and neuropathy in people with a risk factor, such as pregnancy, lactation, HIV infection, alcoholism, diabetes, kidney failure, or malnutrition. [33] People with liver dysfunction are at a higher risk for hepatitis caused by INH, and may need a lower dose. [31]

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