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Plasmapheresis (from the Greek πλάσμα, plasma, something molded, and ἀφαίρεσις aphairesis, taking away) is the removal, treatment, and return or exchange of blood plasma or components thereof from and to the blood circulation. It is thus an extracorporeal therapy, a medical procedure performed outside the body. [1]
Plasma exchange – removal of the liquid portion of blood to remove harmful substances. The plasma is replaced with a replacement solution. The plasma is replaced with a replacement solution. LDL apheresis – removal of low density lipoprotein in patients with familial hypercholesterolemia .
Erythrocytapheresis can also be used for blood donations. The procedure is commonly done using automated red blood cell collection which involves the removal of two units of red blood cells. This includes either two standard units of red blood cells or one unit plus of red blood cells and another of either plasma or platelets.
In conditions such as neonatal polycythemia, a specific amount of the child’s blood is removed and replaced with normal saline, plasma (the clear liquid portion of blood), or an albumin solution. This decreases the total number of red blood cells in the body and makes it easier for blood to flow through the body. [5]
This procedure has been deemed controversial at times, especially when used by athletes.In 2005, the World Anti-Doping Agency ruled that blood-spinning could be used to introduce banned substances, [2] and in 2010 the agency went as far as banning the use of intramuscular injections of PRP in competitive athletes amid some concerns that it boosted performance-enhancing growth factors. [3]
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Since the machine used to perform the procedure uses suction to draw blood out of a donor's body, some people who can give whole blood may have veins too small for platelet donation. Blood accounts for about 8% of body weight, so a 50 kg (110 lb) donor has about four liters of blood.
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