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  2. Ceftolozane/tazobactam - Wikipedia

    en.wikipedia.org/wiki/Ceftolozane/tazobactam

    Ceftolozane–tazobactam is available as a 2:1 fixed combination (such that a 1.5 g dose of ceftolozane–tazobactam is composed of 1 g of ceftolozane and 500 mg of tazobactam). [17] Ceftolozane-tazobactam is administered intravenously.

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  4. FDA Grants Fast Track Designation for Cubist's Late-Stage ...

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  5. FDA Grants Fast Track Designation for Cubist's Late-Stage ...

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  6. Ceftazidime/avibactam - Wikipedia

    en.wikipedia.org/wiki/Ceftazidime/avibactam

    Avibactam inhibits Klebsiella pneumoniae carbapenemases (KPCs), and AmpC-type β-lactamases, which are resistant to the other clinically available β-lactamases, tazobactam and clavulanic acid. [ 15 ]

  7. β-Lactam antibiotic - Wikipedia

    en.wikipedia.org/wiki/Β-Lactam_antibiotic

    The addition of tazobactam to piperacillin has enhanced its stability against a wide range of β-lactamase enzymes including some Extended-Spectrum β-lactamases. [20] Other β-lactamase inhibitors such as boronic acids are being studied in which they irreversibly bind to the active site of β-lactamases. This is a benefit over clavulanic acid ...

  8. Cubist Obtains Remaining Rights to Ceftolozane from Astellas

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  9. Cephalosporin - Wikipedia

    en.wikipedia.org/wiki/Cephalosporin

    Ceftolozane is an option for the treatment of complicated intra-abdominal infections and complicated urinary tract infections. It is combined with the β-lactamase inhibitor tazobactam , as multi-drug resistant bacterial infections will generally show resistance to all β-lactam antibiotics unless this enzyme is inhibited.

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