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Finasteride—which is also approved to treat enlarged prostate symptoms under the name Proscar—can be used alone or in combination with other hair loss treatments, like platelet-rich plasma ...
In one-year clinical trials of Proscar (finasteride 5mg), men who used the drug at a daily dose of 5mg reported breast enlargement at a rate of 0.5 percent (compared to 0.1 percent in the placebo ...
After using finasteride at a 5mg daily dose for one year, men reported the following side effects: ED (reported by 8.1 percent of men) Decreased libido (reported by 6.4 percent of men)
Finasteride is marketed primarily under the brand names Propecia, for pattern hair loss, and Proscar, for BPH, both of which are products of Merck & Co. [99] There is 1 mg of finasteride in Propecia and 5 mg in Proscar. Merck's patent on finasteride for the treatment of BPH expired in June 2006. [100]
A report by Epic Research, conducted on behalf of NBC News, found that the number of men in the U.S. with finasteride prescriptions increased nearly 200% in the last seven years.
Finasteride (brand names Proscar, Propecia) inhibits the function of two of the isoenzymes (types 2 and 3) of 5α-reductase. [ 6 ] [ 7 ] It decreases circulating DHT levels by up to about 70%. [ 8 ] Dutasteride (brand name Avodart) inhibits all three 5α-reductase isoenzymes and can decrease DHT levels by 95%.
Finasteride can cause side effects just like any other drug. But changes in testosterone levels are probably not to blame for any changes in function you might experience from the use of finasteride.
Dutasteride (Avodart) was the second steroidal 5α-reductase approved after finasteride. It is a competitive inhibitor of all three 5α-reductase isoenzymes [4] and it inhibits types 1 and 2 better than finasteride, leading to it causing further reduction in DHT, with >90% reduced DHT levels following 1 year of oral administration. [1]
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