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  2. Adrenergic receptor - Wikipedia

    en.wikipedia.org/wiki/Adrenergic_receptor

    Epinephrine (adrenaline) reacts with both α- and β-adrenoreceptors, causing vasoconstriction and vasodilation, respectively. Although α receptors are less sensitive to epinephrine, when activated at pharmacologic doses, they override the vasodilation mediated by β-adrenoreceptors because there are more peripheral α 1 receptors than β ...

  3. Adrenaline - Wikipedia

    en.wikipedia.org/wiki/Adrenaline

    Adrenaline, also known as epinephrine, is a hormone and medication [10] [11] which is involved in regulating visceral functions ... Vasoconstriction and vasodilation:

  4. Vasoconstriction - Wikipedia

    en.wikipedia.org/wiki/Vasoconstriction

    Vasoconstriction is the narrowing of the blood vessels resulting from contraction of the muscular wall of the vessels, in particular the large arteries and small arterioles. The process is the opposite of vasodilation , the widening of blood vessels.

  5. Alpha-1 adrenergic receptor - Wikipedia

    en.wikipedia.org/wiki/Alpha-1_adrenergic_receptor

    In smooth muscle cells of blood vessels the principal effect of activation of these receptors is vasoconstriction.Blood vessels with α 1-adrenergic receptors are present in the skin, the sphincters [4] of gastrointestinal system, kidney (renal artery) [5] and brain. [6]

  6. Alpha-2 adrenergic receptor - Wikipedia

    en.wikipedia.org/wiki/Alpha-2_adrenergic_receptor

    The α 2-adrenergic receptor binds both norepinephrine released by sympathetic postganglionic fibers and epinephrine (adrenaline) released by the adrenal medulla, binding norepinephrine with slightly higher affinity. [4] It has several general functions in common with the α 1-adrenergic receptor, but also has specific effects of its own.

  7. Vascular smooth muscle - Wikipedia

    en.wikipedia.org/wiki/Vascular_smooth_muscle

    Agonists of alpha-2 receptors in the vascular smooth muscle lead to vasoconstriction. However, in clinical practice drugs applied intravenously that are agonists of alpha-2 receptors such as clonidine lead to powerful vasodilation, which causes a decrease in blood pressure by presynaptic activation of the receptors in the sympathetic ganglia ...

  8. Vascular resistance - Wikipedia

    en.wikipedia.org/wiki/Vascular_resistance

    When environmental changes occur (e.g. exercise, immersion in water), neuronal and hormonal signals, including binding of norepinephrine and epinephrine to the α1 receptor on vascular smooth muscles, cause either vasoconstriction or vasodilation. Because resistance is inversely proportional to the fourth power of vessel radius, changes to ...

  9. Epinephrine (medication) - Wikipedia

    en.wikipedia.org/wiki/Epinephrine_(medication)

    Epinephrine, also known as adrenaline, is a medication and hormone. [10] [11] As a medication, it is used to treat several conditions, including anaphylaxis, cardiac arrest, asthma, and superficial bleeding. [8] Inhaled epinephrine may be used to improve the symptoms of croup. [12] It may also be used for asthma when other treatments are not ...

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