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Bronchiolitis obliterans (BO), also known as obliterative bronchiolitis, constrictive bronchiolitis and popcorn lung, is a disease that results in obstruction of the smallest airways of the lungs (bronchioles) due to inflammation. [1] [6] Symptoms include a dry cough, shortness of breath, wheezing and feeling tired. [1]
Popcorn Lung is a debilitating and irreversible respiratory disease which causes "scarring in tiny air sacs in the lungs that lead to excessive coughing and shortness of breath" similar to that ...
Diacetyl occurs naturally in alcoholic beverages and some cheeses and is added as a flavoring to some foods to impart its buttery flavor. Chronic inhalation exposure to diacetyl fumes is a causative agent of the lung disease bronchiolitis obliterans, commonly known as "popcorn lung".
Exposure to diacetyl produces morphological liver alterations according to animal studies. [142] Diacetyl and acetyl-propionyl have been reported in concentrations above those recommended by the US National Institute for Occupational Safety and Health. [238] Diacetyl is reported at lower levels in e-cigarettes than in traditional cigarettes. [238]
While patchy bilateral disease is typical, there are unusual variants of organizing pneumonia where it may appear as multiple nodules or masses. One rare presentation, focal organizing pneumonia, may be indistinguishable from lung cancer based on imaging alone, requiring biopsy or surgical resection to make the diagnosis. [20]
Lung cancer survival has not improved much in the last 50 years, according to Cancer Research UK, with less than one in 10 (9.5 per cent) of people diagnosed with the disease surviving for 10 ...
The lung disease bronchiolitis obliterans is attributed to prolonged exposure to diacetyl, e.g. in an industrial setting. [2] [3] Workers in several factories that manufacture artificial butter flavoring have been diagnosed with bronchiolitis obliterans, a rare and serious disease of the lungs. [2]
Bronchiolitis obliterans, or “popcorn lung,” is a condition where the smallest pathways in the lungs become inflamed, resulting in frequent coughing and shortness of breath.