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A number of diseases can cause bone pain, including the following: Endocrine, such as hyperparathyroidism, osteoporosis, kidney failure. [7]Gastrointestinal or systemic, such as celiac disease and non-celiac gluten sensitivity (both often occur without obvious digestive symptoms), inflammatory bowel disease (including Crohn's disease and ulcerative colitis).
Chronic recurrent multifocal osteomyelitis (CRMO) is a rare condition (1:1,000,000), in which the bones have lesions, inflammation, and pain.It is called multifocal because it can appear in different parts of the body, primarily bones, and osteomyelitis because it is very similar to that disease, although CRMO appears to be without any infection.
Fibrodysplasia ossificans progressiva (/ ˌ f aɪ b r oʊ d ɪ ˈ s p l eɪ ʒ (i) ə ɒ ˈ s ɪ f ɪ k æ n z p r ə ˈ ɡ r ɛ s ɪ v ə /; [1] abbr. FOP), also called Münchmeyer disease or formerly myositis ossificans progressiva, is an extremely rare connective tissue disease in which fibrous connective tissue such as muscle, tendons, and ligaments turn into bone tissue (ossification).
Conditions that cause hip pain can also cause related symptoms, such as: Stiffness and limited range of motion through the hip. ... Since osteoporosis causes loss of bone mineral density, it makes ...
Cancer-related pain can be caused by metastases, the tumour itself, inflamed or eroding bone viscera or nerves, or pain related to cancer treatments. [15] The term “cancer-related pain” only indicates that pain is related to cancer and does not imply the exact cause of the pain. [16]
Degenerative disc disease occurs over time when the discs within each vertebra in the neck begin to fall apart and begin to disintegrate. Because each vertebra can cause pain in different areas of the body, the pain from the disease can be sensed in the back, leg, neck area, or even the arms.
The cells of our bone that is involved in bone formation and bone breakdown is osteoblast and osteoclast respectively. Osteoclasts are cells of bones that promote bone demineralization or bone resorption. [3] In contrast, Osteoblast promotes calcium absorption by the bone therefore, promoting bone mineralization and formation of new bones. [2]
Other conditions such as Paget’s disease of the bone and a rare genetic condition called Li-Fraumeni syndrome is also cited as potential causes of bone cancer by the NHS.