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Cyclobenzaprine is a tricyclic compound of the dibenzocycloheptene group. It is very similar in chemical structure to tricyclic antidepressants like amitriptyline and imipramine, which are likewise dibenzocycloheptenes. [6] Cyclobenzaprine differs from amitriptyline in structure only by the presence of a single double bond within the tricyclic ...
The pregnancy category of a medication is an assessment of the risk of fetal injury due to the pharmaceutical, if it is used as directed by the mother during pregnancy. It does not include any risks conferred by pharmaceutical agents or their metabolites in breast milk .
[2] [6] Cyclizine appears to be safe during pregnancy but has not been well studied. [7] It is in the anticholinergic and antihistamine family of medications. [3] [6] Cyclizine was discovered in 1947. [8] It is on the World Health Organization's List of Essential Medicines. [9] In the United States it is available over the counter. [6]
Topical nicotinamide and topical zinc are safe, however, there are no FDA pregnancy category ratings. [27] [28] Topical salicylic acid and topical dapsone are classified as FDA pregnancy category C. [23] [28] Acne medications to avoid during pregnancy include oral isotretinoin and topical tazarotene as there have been reports of birth defects.
The clinical effectiveness of methocarbamol compared to other muscle relaxants is not well known. [12] One trial of methocarbamol versus cyclobenzaprine, a well-studied muscle relaxant, in those with localized muscle spasm found there were no significant differences in their effects on muscle spasm, limitation of motion, or limitation of daily activities.
That said, Vanessa Rissetto, R.D., co-founder of the virtual nutrition care service Culina Health, believes the FDA's move is a positive step forward."Early-stage cancers are on the rise across ...
The growing popularity of drugs like Ozempic, Mounjaro and Wegovy, designed to help people with Type 2 diabetes and obesity, has raised new questions about what those drugs could mean for ...
Safety during pregnancy and breast-feeding [ edit ] Eperisone has not been established to be safe for use by pregnant women; therefore the drug should not be used in pregnant women, or women who may be pregnant, if the expected therapeutic benefits will outweigh the possible risks associated with treatment.