Search results
Results from the WOW.Com Content Network
Glucose deficiencies such as hypoglycaemia reduce available energy for the brain and impair all cognitive processes and performance. [8] [12] [13] Additionally, situations with high cognitive demand, such as learning a new task, increase brain glucose utilization, depleting blood glucose stores and initiating the need for supplementation. [8]
“Vitamin B12 deficiency can cause cognitive impairment, including impairments in thinking,” says Dr. Scott Kaiser, a geriatrician and director of Geriatric Cognitive Health for the Pacific ...
this disease may even occur in some people with normal, or even high blood thiamine levels, or people with deficiencies in intracellular transport of this vitamin. [11] Selected genetic mutations, including presence of the X-linked transketolase-like 1 gene, SLC19A2 thiamine transporter protein mutations, and the aldehyde dehydrogenase-2 gene ...
Frequently, secondary to thiamine deficiency and subsequent cytotoxic edema in Wernicke encephalopathy, patients will have marked degeneration of the mammillary bodies. Thiamine (vitamin B 1) is an essential coenzyme in carbohydrate metabolism and is also a regulator of osmotic gradient. Its deficiency may cause swelling of the intracellular ...
Vitamin B 12 deficiency can be determined, but not always. [14] This means it measures forms of vitamin B 12 that are "active" and can be used by the body, as well as the "inactive" forms, which cannot. [151] Vitamin B 12 deficiency can be found within normal levels, so clinical symptoms should be taken into account when a diagnosis is made. [2]
Korsakoff syndrome (KS) [1] is a disorder of the central nervous system characterized by amnesia, deficits in explicit memory, and confabulation.This neurological disorder is caused by a deficiency of thiamine (vitamin B 1) in the brain, and it is typically associated with and exacerbated by the prolonged, excessive ingestion of alcohol. [2]
Gestational vitamin D deficiency in rats is associated with reduced levels of neurotrophic factors NGF and GDNF. [7] NGF is the nerve growth factor , which is involved in neurotransmission . GDNF is the glial cell lined derived neurotrophic factor, which is involved in the survival and differentiation of dopaminergic neurons.
The recommended investigations for cognitive impairment include: blood tests (for anemia, vitamin deficiency, thyrotoxicosis, infection, among others), chest xray, ECG, and neuroimaging, preferably a scan with a functional or metabolic sensitivity beyond a simple CT or MRI.