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Cinchonism is a pathological condition caused by an overdose of quinine or its natural source, cinchona bark. Quinine and its derivatives are used medically to treat malaria and lupus erythematosus. In much smaller amounts, quinine is an ingredient of tonic drinks, acting as a bittering agent. Cinchonism can occur from therapeutic doses of ...
In the United States, the US Food and Drug Administration (FDA) limits the quinine content in tonic water to 83 ppm [8] (83 mg per liter), while the daily therapeutic dose of quinine is in the range of 500–1000 mg, [9] and 10 mg/kg every eight hours for effective malaria prevention (2,100 mg daily for a 70-kilogram (150 lb) adult). [10]
Quinine is also used as an ingredient in tonic water and other beverages to impart a bitter taste. [8] Common side effects include headache, ringing in the ears, vision issues, and sweating. [5] More severe side effects include deafness, low blood platelets, and an irregular heartbeat. [5] Use can make one more prone to sunburn. [5]
Tonic water is a carbonated soda water with dissolved quinine. It has similarities to club soda, as well as some key differences.
You can still find quinine in modern tonic water, but in significantly smaller amounts than older recipes. This bitter and sweet beverage adds a layered flavor that complements nearly any spirit.
However, the quinine article states that "tonic water" has existed since ancient times (i.e., that Peruvians used cinchona-bark tea to avoid shivering, and that it became popular in Europe in the 17th century after its anti-malarial side-effect was lucked upon during attempts to treat malarial symptoms, implying carbonation has nothing to do ...
The water is expensive, possibly dangerous, and insulting to people struggling for clean, treated water all over the world. So save yourself the $16 and enjoy the clean water we already have ...
Quinine is effective, but not recommended because of the potential for serious side effects. [2] Calcium channel blockers may be effective, although the evidence for their use is weak. [2] There is little evidence supporting other therapies. [2]