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Melioidosis is an infectious disease caused by a gram-negative bacterium called Burkholderia pseudomallei. [1] Most people exposed to B. pseudomallei experience no symptoms; however, those who do experience symptoms have signs and symptoms that range from mild, such as fever and skin changes, to severe with pneumonia, abscesses, and septic shock that could cause death. [1]
Re-infection is a recurrence of symptoms due to an infection with a new strain of Burkholderia pseudomallei following the eradication therapy of melioidosis. Meanwhile, relapse are those who presented with melioidosis symptoms due to failure to clear the infection in the bloodstream after completion of eradication therapy.
Due to the high mortality rate in humans and the small number of organisms required to establish infection, B. mallei is regarded as a potential biological warfare or bioterrorism agent, as is the closely related organism, B. pseudomallei, the causative agent of melioidosis.
Major Alfred Whitmore (1876–1946) was an English pathologist who, together with C.S. Krishnaswami, identified Burkholderia pseudomallei, the causative agent of melioidosis (also known as "Whitmore's disease") in opium addicts in Rangoon in 1911.
The First Symptoms of Monkeypox to Look For “Monkeypox usually begins with flu-like symptoms, including fever, chills, achiness, and swelling of lymph nodes,” says Dr. Jay Varma, MD ...
The overall decrease in cardiac function leads to a plethora of symptoms. [2] This multisystem disease was often misdiagnosed, with a corrected analysis only during autopsy. Advancements of technologies have increased earlier accuracy of diagnosis. Cardiac amyloidosis has multiple sub-types including light chain, familial, and senile. [3]
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Impetigo was originally described and differentiated by the English dermatologist William Tilbury Fox around 1864. [28] The word impetigo is the generic Latin word for 'skin eruption', and it stems from the verb impetere 'to attack' (as in impetus ). [ 29 ]