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Xerostomia, also known as dry mouth, is a subjective complaint of dryness in the mouth, which may be associated with a change in the composition of saliva, or reduced salivary flow, or have no identifiable cause. [1] This symptom is very common and is often seen as a side effect of many types of medication.
Hypersalivation can contribute to drooling if there is an inability to keep the mouth closed or difficulty in swallowing (dysphagia) the excess saliva, which can lead to excessive spitting. Hypersalivation also often precedes emesis (vomiting), where it accompanies nausea (a feeling of needing to vomit).
However, they can also cause constipation, dry mouth, and fatigue. Dolasetron ( Anzemet ) can be administered in tablet form or in an injection. Granisetron ( Kytril , Sancuso ) can be administered in tablet (Kytril), oral solution (Kytril), injection (Kytril), or in a single transdermal patch to the upper arm (SANCUSO).
Cevimeline is used in the treatment of xerostomia (dry mouth) [1] [2] and Sjögren's syndrome. [1] It increases the production of saliva. [2] Side effects.
Medications include ondansetron, granisetron, and dolasetron. Anticholinergics can be used as a long-acting patch placed behind the patient's ear. Adverse effects include dry mouth and blurry vision. Care must be taken when handling the patch, as transfer of medication to the eye can induce pupillary dilation. Avoid use in elderly patients.
It is used to prevent or treat dry mouth, particularly in Sjögren syndrome, but also as a side effect of radiation therapy for head and neck cancer. [17] It may be used to help differentiate Adie syndrome from other causes of unequal pupil size. [18] [19] It may be used to treat a form of dry eye called aqueous deficient dry eye (ADDE) [20]
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