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A pregnancy test is used to determine whether a female is pregnant or not. The two primary methods are testing for the female pregnancy hormone (human chorionic gonadotropin (hCG)) in blood or urine using a pregnancy test kit, and scanning with ultrasonography. [1] Testing blood for hCG results in the earliest detection of pregnancy. [2]
During this method of prenatal testing, a sample of chorionic villi is removed from the placenta to be tested. This test is performed 10–13 weeks into pregnancy and results are ready 7–14 days after the test was done. [18] Another test using blood taken from the fetal umbilical cord is percutaneous umbilical cord blood sampling.
Blood and urine tests can detect pregnancy by 11 and 14 days, respectively, after fertilization. [78] [79] Blood pregnancy tests are more sensitive than urine tests (giving fewer false negatives). [80] Home pregnancy tests are urine tests, and normally detect a pregnancy 12 to 15 days after fertilization. [81]
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A few days after the injection, the animal would be dissected and the size of her ovaries examined. The rabbit test became a widely used bioassay (animal-based test) to test for pregnancy. The term "rabbit test" was first recorded in 1949, and was the origin of a common euphemism, "the rabbit died", for a positive pregnancy test. [4]
For example, two O blood type parents can produce a child only with an O blood type, and two parents with a B blood type can produce a child with either a B or an O blood type. This often led to inconclusive results, as 30% of the entire population can be excluded from being the possible parent under this form of testing. [10]
Human chorionic gonadotropin is a glycoprotein composed of 237 amino acids with a molecular mass of 36.7 kDa, approximately 14.5kDa αhCG and 22.2kDa βhCG. [4]It is heterodimeric, with an α (alpha) subunit identical to that of luteinizing hormone (LH), follicle-stimulating hormone (FSH), thyroid-stimulating hormone (TSH), and a β (beta) subunit that is unique to hCG.
Before immunological pregnancy tests were developed in the 1960s, women relied on urine-based pregnancy tests using animals, ranging from mice to frogs. [1] [2] Advancements in medical technology have enabled women to accurately check their pregnancy status by using 'pee-on-a-stick' pregnancy test kits at home. Before these accessible and ...
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