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Gout causes painful swelling, typically only impacting one joint. Its symptoms can come and go. Periods when gout symptoms are more severe are called gout flares or gout attacks.
Rates of gout approximately doubled between 1990 and 2010. [17] This rise is believed to be due to increasing life expectancy, changes in diet and an increase in diseases associated with gout, such as metabolic syndrome and high blood pressure. [25] Factors that influence rates of gout include age, race, and the season of the year.
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The post Managing Out-of-Control Chronic Gout: Going Beyond Oral Treatments appeared first on Reader's Digest. Do you sometimes have severe, unexplained pain in your joints, particularly in your ...
Creatine is produced by the enzyme guanidinoacetate methyltransferase (GAMT). After production in the liver and kidneys, creatine is transported to organs and tissues with high energy demands, most commonly the brain and skeletal muscles. In addition to endogenous production, creatine can be obtained from dietary sources or supplementation.
Creatine supplements are marketed in ethyl ester, gluconate, monohydrate, and nitrate forms. [40] Creatine supplementation for sporting performance enhancement is considered safe for short-term use but there is a lack of safety data for long term use, or for use in children and adolescents. [41] Some athletes choose to cycle on and off creatine ...
What causes gout? The condition is caused by a buildup of uric acid in the body. Uric acid forms when the body breaks down purines, a chemical compound that cells use to form DNA and RNA.
Creatine conversion to phosphocreatine is catalysed by creatine kinase; spontaneous formation of creatinine occurs during the reaction. [7] Creatinine is removed from the blood chiefly by the kidneys, primarily by glomerular filtration, but also by proximal tubular secretion. Little or no tubular reabsorption of creatinine occurs. If filtration ...
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