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Wrinkly skin syndrome (WSS) is a rare genetic condition characterized by sagging, wrinkled skin, low skin elasticity, and delayed fontanelle (soft spot) closure, along with a range of other symptoms. [1] The disorder exhibits an autosomal recessive inheritance pattern with mutations in the ATP6V0A2 gene, leading to abnormal glycosylation events ...
A wrinkle, also known as a rhytid, is a fold, ridge or crease in an otherwise smooth surface, such as on skin or fabric. Skin wrinkles typically appear as a result of ageing processes such as glycation , [ 1 ] habitual sleeping positions, [ 2 ] loss of body mass, sun damage, [ 3 ] or temporarily, as the result of prolonged immersion in water .
Wrinkly skin syndrome; Writer's cramp; Wt limb blood syndrome; Wyburn–Mason's syndrome This page was last edited on 14 March 2022, at 17:45 (UTC). Text is ...
Wrinkly skin syndrome This page was last edited on 23 January 2021, at 04:54 (UTC). Text is available under the Creative Commons Attribution-ShareAlike 4.0 ...
Actinic elastosis usually appears as thickened, dry, wrinkled skin. Several clinical variants have been recorded. One of the most readily identifiable is the thickened, deeply fissured skin seen on the back of the chronically sun-exposed neck, known as cutis rhomboidalis nuchae. [2]
Gerodermia osteodysplastica is characterized by symptoms and features which affect the connective tissues, skin and skeletal system. [citation needed]These are: wrinkly, loose skin over the face, abdomen, and extremities (hands, feet) on the dorsal sides usually worsened by chronic joint laxity and hyperextensibility; [8] [9] fragmented elastic fibers of the skin that are reduced in number ...
Signs and symptoms of this progressive disease tend to become more marked as the child ages. Later, the condition causes wrinkled skin, kidney failure, loss of eyesight, and atherosclerosis and other cardiovascular problems. [12] Scleroderma, a hardening and tightening of the skin on trunk and extremities of the body, is prevalent.
The skin weighs an average of four kilograms, covers an area of two square metres, and is made of three distinct layers: the epidermis, dermis, and subcutaneous tissue. [1] The two main types of human skin are: glabrous skin, the hairless skin on the palms and soles (also referred to as the "palmoplantar" surfaces), and hair-bearing skin. [3]