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Amitriptyline is effective for depression, [23] but it is rarely used as a first-line antidepressant due to its higher toxicity in overdose and generally poorer tolerability. [24] It can be tried for depression as a second-line therapy, after the failure of other treatments. [ 13 ]
Moclobemide is regarded as a generally safe antidepressant and due to its favorable side effect profile, it can be considered a first-line therapeutic antidepressant. [56] The rate of incidence of side effects of moclobemide is low, [ 23 ] with insomnia , headache and dizziness being the most commonly reported side effects in the initial stages ...
He pointed out that the first-line alternative to medication is psychotherapy, which does not have superior efficacy. [105] Antidepressants in general are as effective as psychotherapy for major depression, and this conclusion holds true for both severe and mild forms of MDD. [106] [107] In contrast, medication gives better results for dysthymia.
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The guidelines recommended that antidepressant treatment be considered: For people with a history of moderate or severe depression. For people with mild depression that has been present for an extended period. As a first-line treatment for moderate to severe depression.
Antidepressants are recommended by the UK National Institute for Health and Care Excellence (NICE) as a first-line treatment of severe depression and for the treatment of mild-to-moderate depression that persists after conservative measures such as cognitive therapy. [10]
Sertraline, sold under the brand name Zoloft among others, is an antidepressant medication of the selective serotonin reuptake inhibitor (SSRI) class [10] used to treat major depressive disorder, generalized anxiety disorder, social anxiety disorder, obsessive–compulsive disorder (OCD), panic disorder, and premenstrual dysphoric disorder. [11]
Gestational diabetes is a form of diabetes that is first diagnosed during pregnancy and can accordingly cause high blood sugar that affects the woman and the baby. [9] In 10 - 20% of women whose diet and exercise are not adequate enough to control blood sugar, insulin injections may be required to lower blood sugar levels. [ 9 ]
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