Search results
Results from the WOW.Com Content Network
Atorvastatin, sold under the brand name Lipitor among others, is a statin medication used to prevent cardiovascular disease in those at high risk and to treat abnormal lipid levels. [6] For the prevention of cardiovascular disease, statins are a first-line treatment. [ 6 ]
Ezetimibe/atorvastatin (trade names Liptruzet, Atozet) is a cholesterol lowering combination drug. In the United States, it was approved in May 2013, by the Food and Drug Administration for the treatment of elevated low-density lipoprotein (LDL) in patients with primary or mixed hyperlipidemia as adjunctive therapy to diet. [ 1 ]
The best-selling statin is atorvastatin, also known as Lipitor, which in 2003 became the best-selling pharmaceutical in history. [12] The manufacturer Pfizer reported sales of US$12.4 billion in 2008. [13] Patient compliance with statin usage is problematic despite robust evidence of the benefits. [14] [15]
Type 2 statins form polar interaction between the fluorine atom on the fluorophenyl group and the guanidinium group of Arg 590. [11] In addition to these interactions atorvastatin and rosuvastatin also form unique hydrogen bonds between Ser 565 residue and either a carbonyl oxygen atom (atorvastatin) or a sulfone oxygen atom (rosuvastatin).
AOL latest headlines, entertainment, sports, articles for business, health and world news.
The British National Formulary (BNF) is a United Kingdom (UK) pharmaceutical reference book that contains a wide spectrum of information and advice on prescribing and pharmacology, along with specific facts and details about many medicines available on the UK National Health Service (NHS).
Amlodipine/atorvastatin, sold under the brand name Caduet among others, is a fixed-dose combination medication for the treatment of high cholesterol and high blood pressure. It contains a statin and a calcium channel blocker .
The following other wikis use this file: Usage on ar.wikipedia.org أتورفاستاتين; Usage on azb.wikipedia.org اتورواستاتین / املودیپین