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Pellagra is a disease caused by a lack of the vitamin niacin (vitamin B 3). [2] Symptoms include inflamed skin, diarrhea, dementia, and sores in the mouth. [1] Areas of the skin exposed to friction and radiation are typically affected first. [1]
Spies was appointed to the Food and Nutrition Board of National Research Council in 1943, and was a consultant on tropical medicine at Washington's Army Medical School, 1945. He labored with unremitting zeal to put thiamine , nicotinic acid , riboflavin , folic acid , vitamin B12 and thymine (5-methyl uracil) [ 3 ] to use in clinical and ...
A man with pellagra, which is caused by a chronic lack of vitamin B 3 in the diet. Severe deficiency of niacin in the diet causes the disease pellagra, characterized by diarrhea, sun-sensitive dermatitis involving hyperpigmentation and thickening of the skin (see image), inflammation of the mouth and tongue, delirium, dementia, and if left untreated, death. [7]
Common, most foods do not contain vitamin D, indicating that a deficiency will occur unless people get sunlight exposure or eat manufactured foods purposely fortified with vitamin D. Vitamin D deficiency is a known cause of rickets, and has been linked to numerous other health problems. [46] [47] Vitamin E deficiency
Some physicians at the time believed that the disease arose in consequence of bad genes, airborne germs, or miasma resulting from poor sanitary conditions. [6] Goldberger's theory that pellagra was associated with diet contradicted the most widely accepted medical opinion that pellagra was an infectious disease.
Check the environmental impact of what you eat and drink.
Greater weight loss results, including amongst underserved populations, are achieved when proper nutrition is regularly combined with physical exercise and counseling. [4] [12] [14] [15] [16] Dietary and lifestyle changes are effective in limiting excessive weight gain in pregnancy and improve outcomes for both the mother and the child. [17]
Goldsmith is best known for her research on nutritional deficiency diseases, B-complex vitamins, vitamin enrichment of foods, as well as pioneering nutritional training for medical students. [2] Goldsmith discovered the specific roles of dietary folic acid and vitamin B-12 and determined that niacin deficiency was the cause of pellagra .