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While histoplasmosis is the most common cause of mediastinitis, this remains a relatively rare disease. Severe infections can cause hepatosplenomegaly, lymphadenopathy, and adrenal enlargement. [4] Lesions often left calcification nodules as they are healed. [12]
The most frequent findings on a computed tomography (CT) of the chest are multiple primary nodules and/or masses, on a background of mosaic attenuation and airway wall thickening. [2] [9] The nodules have an indolent pattern of growth and are found throughout the lungs. The nodules are typically rounded and well-defined.
Chest X-rays rarely demonstrate nodules or cavities in the lungs, but these images commonly demonstrate lung opacification, pleural effusions, or enlargement of lymph nodes associated with the lungs. [4] Computed tomography scans of the chest are more sensitive than chest X-rays to detect these changes. [4]
A lung nodule or pulmonary nodule is a relatively small focal density in the lung. A solitary pulmonary nodule (SPN) or coin lesion, [1] is a mass in the lung smaller than three centimeters in diameter. A pulmonary micronodule has a diameter of less than three millimetres. [2] There may also be multiple nodules. One or more lung nodules can be ...
Pulmonary cryptococcosis has a worldwide distribution and is commonly underdiagnosed due to limitations in diagnostic capabilities. Since pulmonary nodules are its most common radiological feature, they can clinically and radiologically mimic lung cancer, TB, and other pulmonary mycoses.
The pulmonary alveolar macrophage is a key cellular element in the initiation and perpetuation of lung injury and fibrosis. Many particles activate the inflammasome and induce IL-1 production. The more reactive particles trigger the macrophages to release a number of products that mediate an inflammatory response and initiate fibroblast ...
Hypersensitivity Pneumonitis; Other names: Allergic alveolitis, bagpipe lung, extrinsic allergic alveolitis (EAA) High magnification photomicrograph of a lung biopsy taken showing chronic hypersensitivity pneumonitis (), showing mild thickening of the walls of the small air sacs by invasion of white blood cells.
Caplan syndrome is a nodular condition of the lung occurring in dust-exposed persons with either a history of rheumatoid arthritis (RA) or who subsequently develop RA within the following 5–10 years. [3] The nodules in the lung typically occur bilaterally and peripherally, on a background of simple coal workers' pneumoconiosis. There are ...
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