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  2. When Is the Best Time to Take Metformin? - AOL

    www.aol.com/best-time-metformin-141700387.html

    Taking metformin with food can reduce the risk of gastrointestinal side effects, so try taking it with the same meal each day. If you take one metformin tablet a day, it’s usually recommended ...

  3. How Your Painful Leg Cramps Could Be Signaling a Vitamin ...

    www.aol.com/lifestyle/painful-leg-cramps-could...

    The causes of leg cramps at night can range from nutrient deficiency to tough workouts. Here, experts break down how to prevent and get rid of leg cramps.

  4. Restless leg syndrome: Can vitamins help? An expert ... - AOL

    www.aol.com/vitamins-help-restless-leg-syndrome...

    About one in 10 people have restless leg syndrome, but the cause is a mystery. See what remedies doctors suggest. ... These drugs help you sleep better at night, but they don't eliminate the leg ...

  5. Metformin - Wikipedia

    en.wikipedia.org/wiki/Metformin

    Gastrointestinal upset can cause severe discomfort; it is most common when metformin is first administered, or when the dose is increased. [75] [80] The discomfort can often be avoided by beginning at a low dose (1.0 to 1.7 g/day) and increasing the dose gradually, but even with low doses, 5% of people may be unable to tolerate metformin.

  6. Proximal diabetic neuropathy - Wikipedia

    en.wikipedia.org/wiki/Proximal_diabetic_neuropathy

    Proximal diabetic neuropathy, also known as diabetic amyotrophy, is a complication of diabetes mellitus that affects the nerves that supply the thighs, hips, buttocks and/or lower legs. Proximal diabetic neuropathy is a type of diabetic neuropathy characterized by muscle wasting, weakness, pain, or changes in sensation/numbness of the leg.

  7. Cramp - Wikipedia

    en.wikipedia.org/wiki/Cramp

    A cramp is a sudden, involuntary, painful skeletal muscle contraction [1] [2] or overshortening associated with electrical activity; [3] while generally temporary and non-damaging, they can cause significant pain and a paralysis-like immobility of the affected muscle.

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