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Brain RNA-Seq [160] An RNA-Seq transcriptome and splicing database of glia, neurons, and vascular cells of the cerebral cortex. FusionCancer [161] a database of cancer fusion genes derived from RNA-seq data. Hipposeq a comprehensive RNA-seq database of gene expression in hippocampal principal neurons.
RNA-Seq can also be used to determine exon/intron boundaries and verify or amend previously annotated 5' and 3' gene boundaries. Recent advances in RNA-Seq include single cell sequencing, bulk RNA sequencing, [6] 3' mRNA-sequencing, in situ sequencing of fixed tissue, and native RNA molecule sequencing with single-molecule real-time sequencing. [7]
The fundamental aspect of BRB-seq is the optimized sample barcode primers. Each barcoded nucleotide sequence includes an adaptor for primer annealing, a 14-nt long barcode that assigns a unique identifier to each individual RNA sample, and a random 14-nt long UMI that tags each mRNA molecule with a unique sequence to distinguish between original mRNA transcripts and duplicates that result from ...
Database of long-noncoding RNAs causally implicated in cancer through in vivo, in vitro and other evidence. [15] BIGTranscriptome: High-confidence of coding and noncoding transcriptomes assembled with hundreds of pseudo-stranded and stranded RNA-seq datasets. [16] lncRNAKB
3D structure protein databases, Protein sequence databases MobiDB: Database of intrinsically disordered and mobile proteins: John Moult, Christine Orengo, Predrag Radivojac University of Padua: Italian Government database of intrinsic protein disorder annotation 3D structure protein databases, Protein sequence databases ModBase
This bioinformatics-related article is a stub. You can help Wikipedia by expanding it.
The Reference Sequence (RefSeq) database [1] is an open access, annotated and curated collection of publicly available nucleotide sequences (DNA, RNA) and their protein products. RefSeq was introduced in 2000.
The Expression Atlas is a database maintained by the European Bioinformatics Institute that provides information on gene expression patterns from RNA-Seq and Microarray studies, and protein expression from Proteomics studies. [1]
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