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As mentioned, if two methoxymalonyl CoA molecules are substituted for two malonyl-CoA molecules, they will take place in module 7 and 8 (C13 and C15), and fkbA enzyme will enforce this process. After the last step (module 10) of PKS 1, one molecule of L - pipecolic acid formed from L - lysine and catalyzed through fkbL enzyme synthesizes with ...
Oxymetazoline, sold under the brand name Afrin among others, is a topical decongestant and vasoconstrictor medication. It is available over-the-counter as a nasal spray to treat nasal congestion and nosebleeds, as eye drops to treat eye redness due to minor irritation, and (in the United States) as a prescription topical cream to treat persistent facial redness due to rosacea in adults.
[4] [7] [8] [9] For these reasons, as well as superior potency, tolerability, and pharmacokinetics, bicalutamide is preferred and has largely replaced flutamide and nilutamide in clinical practice. [ 10 ] [ 11 ] [ 12 ] In accordance, bicalutamide is the most widely used antiandrogen in the treatment of prostate cancer .
Polycystic ovary syndrome, or polycystic ovarian syndrome (PCOS), is the most common endocrine disorder in women of reproductive age. [14] The syndrome is named after cysts which form on the ovaries of some women with this condition, though this is not a universal symptom and not the underlying cause of the disorder.
Hydrogen peroxide is a chemical compound with the formula H 2 O 2.In its pure form, it is a very pale blue [5] liquid that is slightly more viscous than water.It is used as an oxidizer, bleaching agent, and antiseptic, usually as a dilute solution (3%–6% by weight) in water for consumer use and in higher concentrations for industrial use.
Spironolactone, the 5α-reductase inhibitor finasteride, and the nonsteroidal antiandrogen flutamide all appear to have similar effectiveness in the treatment of hirsutism. [ 68 ] [ 81 ] [ 82 ] However, some clinical research has found that the effectiveness of spironolactone for hirsutism is greater than that of finasteride but is less than ...
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