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Aldosterone is the main mineralocorticoid steroid hormone produced by the zona glomerulosa of the adrenal cortex in the adrenal gland. [ 4 ] [ 5 ] It is essential for sodium conservation in the kidney, salivary glands, sweat glands, and colon. [ 6 ]
The circumflex artery supplies the posterolateral left ventricle and the anterolateral papillary muscle. It also supplies the sinoatrial nodal artery in 38% of people. It supplies 15–25% of the left ventricle in right-dominant systems. If the coronary anatomy is left-dominant, the circumflex artery supplies 40–50% of the left ventricle.
[4] [5] Aldosterone is largely responsible for the long-term regulation of blood pressure. [6] Aldosterone's effects are on the distal convoluted tubule and collecting duct of the kidney where it causes increased reabsorption of sodium and increased excretion of both potassium (by principal cells) and hydrogen ions (by intercalated cells of the ...
The left coronary artery distributes blood to the left side of the heart, the left atrium and ventricle, and the interventricular septum. The circumflex artery arises from the left coronary artery and follows the coronary sulcus to the left. Eventually, it will fuse with the small branches of the right coronary artery.
Angiotensin II is the major bioactive product of the renin–angiotensin system, binding to receptors on intraglomerular mesangial cells, causing these cells to contract along with the blood vessels surrounding them; and to receptors on the zona glomerulosa cells, causing the release of aldosterone from the zona glomerulosa in the adrenal cortex.
The left coronary artery (LCA, also known as the left main coronary artery, or left main stem coronary artery) is a coronary artery that arises from the aorta above the left cusp of the aortic valve, and supplies blood to the left side of the heart muscle.
About 13% — roughly 3,600 participants — had either a heart attack or stroke, had surgery to fix a narrowed or blocked artery, or died from heart disease over the 30-year follow-up period.
Anatomy photo:20:09-0106 at the SUNY Downstate Medical Center - "Heart: The Left Coronary Artery and its Branches" Anatomy figure: 20:04-02 at Human Anatomy Online, SUNY Downstate Medical Center - "Posterior view of the heart." "Obtuse marginal artery". Medcyclopaedia. GE. Archived from the original on 2012-02-05. Image at texheartsurgeons.com