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Metoprolol is used for a number of conditions, including angina, acute myocardial infarction, supraventricular tachycardia, ventricular tachycardia, congestive heart failure, and prevention of migraine headaches. [4] It is an adjunct in the treatment of hyperthyroidism. [17]
Adrenergic blocking agents are a class of drugs that exhibit its pharmacological action through inhibiting the action of the sympathetic nervous system [1] in the body. The sympathetic nervous system(SNS) is an autonomic nervous system that we cannot control by will.
The first-dose reaction can also result in tachycardia and orthostatic hypotension, which is characterised by a feeling of extreme dizziness that gets worse with an upright posture. [1] Intravascular volume reduction , or concomitant use of other antihypertensive drugs can also lead to reflex tachycardia and orthostatic hypotension .
Supraventricular tachycardia (SVT) is an umbrella term for fast heart rhythms arising from the upper part of the heart. [2] This is in contrast to the other group of fast heart rhythms – ventricular tachycardia , which start within the lower chambers of the heart . [ 2 ]
Superficial vein thrombosis (SVT) is a blood clot formed in a superficial vein, a vein near the surface of the body. Usually there is thrombophlebitis , which is an inflammatory reaction around a thrombosed vein, presenting as a painful induration (thickening of the skin) with redness .
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Posttraumatic stress disorder (PTSD) is theorized to be the result of neurological patterns caused by adrenaline and fear in the brain. By administering beta blockers which can cross the blood brain barrier immediately following a traumatic event, as well as over the next couple weeks, the formation of PTSD has been reduced in clinical studies.
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