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Essential tremor (ET), also called benign tremor, familial tremor, and idiopathic tremor, is a medical condition characterized by involuntary rhythmic contractions and relaxations (oscillations or twitching movements) of certain muscle groups in one or more body parts of unknown cause. [ 6 ] It is typically symmetrical, and affects the arms ...
Specialty. Neurology. Intention tremor is a dyskinetic disorder characterized by a broad, coarse, and low-frequency (below 5 Hz) tremor evident during deliberate and visually-guided movement (hence the name intention tremor). An intention tremor is usually perpendicular to the direction of movement. When experiencing an intention tremor, one ...
Ali R. Rezai (born 1965) [1] is an Iranian-born American neurosurgeon and neuroscientist. [2] [3] His work and research has focused on neuromodulation treatments for patients with neurological and mental health conditions, [4] including neuromodulation techniques such as deep brain stimulation (DBS) through brain chip implants to treat Parkinson's disease tremors, obsessive–compulsive ...
Deep brain stimulation (DBS) is a surgical procedure that implants a neurostimulator and electrodes which sends electrical impulses to specified targets in the brain responsible for movement control. The treatment is designed for a range of movement disorders such as Parkinson's disease, essential tremor, and dystonia, as well as for certain ...
A tremor is an involuntary, [1] somewhat rhythmic, muscle contraction and relaxation involving oscillations or twitching movements of one or more body parts. It is the most common of all involuntary movements and can affect the hands, arms, eyes, face, head, vocal folds, trunk, and legs. Most tremors occur in the hands.
SAGE-324. SAGE-324, also known as BIIB124, is an experimental drug. It is a neurosteroid that works as a GABA A receptor positive allosteric modulator. [1][2][3] SAGE-324 was being developed by Biogen for the treatment of essential tremor. [4] Its development was discontinued in 2024 due to lack of efficacy in Phase 2 clinical trials.
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