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Leucine (symbol Leu or L) [3] is an essential amino acid that is used in the biosynthesis of proteins.Leucine is an α-amino acid, meaning it contains an α-amino group (which is in the protonated −NH 3 + form under biological conditions), an α-carboxylic acid group (which is in the deprotonated −COO − form under biological conditions), and a side chain isobutyl group, making it a non ...
Niemann–Pick type C (NPC) (colloquially, "Childhood Alzheimer's " [1]) is a lysosomal storage disease associated with mutations in NPC1 and NPC2 genes. Niemann–Pick type C affects an estimated 1:150,000 people. [2] Approximately 50% of cases present before 10 years of age, but manifestations may first be recognized as late as the sixth decade.
A branched-chain amino acid (BCAA) is an amino acid having an aliphatic side-chain with a branch (a central carbon atom bound to three or more carbon atoms). Among the proteinogenic amino acids, there are three BCAAs: leucine, isoleucine, and valine. [1] Non-proteinogenic BCAAs include 2-aminoisobutyric acid and alloisoleucine.
The leucines are primarily the four isomeric amino acids: leucine, isoleucine, tert -leucine (terleucine, pseudoleucine) and norleucine. [1] Being compared with the four butanols, they could be classified as butyl-substituted glycines; they represent all four possible variations. Leucine and isoleucine belong to the proteinogenic amino acids ...
Acetylleucine. Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Acetylleucine is a modified amino acid used in the treatment of vertigo [2] and cerebellar ataxia. Two forms exist: Acetyl-DL-leucine (sold under the brand Tanganil, among other) and Acetyl-L-leucine.
Infobox references. β-Leucine ( beta-leucine) is a beta amino acid and positional isomer of L -leucine which is naturally produced in humans via the metabolism of L -leucine by the enzyme leucine 2,3-aminomutase. [1] [2] [3] In cobalamin (vitamin B 12) deficient individuals, plasma concentrations of β-leucine are elevated. [3]
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