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Frequency. 1 per 1000 people [8] Pernicious anemia is a disease where not enough red blood cells are produced due to a deficiency of vitamin B 12. [5] Those affected often have a gradual onset. [5] The most common initial symptoms are feeling tired and weak. [4]
Megaloblastic anemia is a type of macrocytic anemia. An anemia is a red blood cell defect that can lead to an undersupply of oxygen. [1] Megaloblastic anemia results from inhibition of DNA synthesis during red blood cell production. [2] When DNA synthesis is impaired, the cell cycle cannot progress from the G2 growth stage to the mitosis (M) stage.
6% (< 60 years old), 20% (> 60 years old) [4] Vitamin B12 deficiency, also known as cobalamin deficiency, is the medical condition in which the blood and tissue have a lower than normal level of vitamin B 12. [5] Symptoms can vary from none to severe. [1] Mild deficiency may have few or absent symptoms. [1]
54,200 (2015) [7] Iron-deficiency anemia is anemia caused by a lack of iron. [3] Anemia is defined as a decrease in the number of red blood cells or the amount of hemoglobin in the blood. [3] When onset is slow, symptoms are often vague such as feeling tired, weak, short of breath, or having decreased ability to exercise. [1]
The word anemia used alone implies widespread effects from blood that either is too scarce (e.g., blood loss) or is dysfunctional in its oxygen-supplying ability (due to whatever type of hemoglobin or erythrocyte problem). In contrast, the word ischemia refers solely to the lack of blood (poor perfusion). Thus ischemia in a body part can cause ...
None, immunosuppressants, platelet transfusion, surgical removal of the spleen [1] In hematology, thrombocytopenia is a condition characterized by abnormally low levels of platelets (also known as thrombocytes) in the blood. [2] Low levels of platelets in turn may lead to prolonged or excessive bleeding.
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