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From 2002 to 2010, a team at the Hungarian Academy of Science created a strain of Escherichia coli called MDS42, which is now sold by Scarab Genomics of Madison, WI under the name of "Clean Genome E. coli", [123] where 15% of the genome of the parental strain (E. coli K-12 MG1655) were removed to aid in molecular biology efficiency, removing IS ...
E. coli (EIEC) found only in humans Bloody or nonbloody EIEC infection causes a syndrome that is identical to shigellosis, with profuse diarrhea and high fever. Enterohemorrhagic E. coli (EHEC) found in humans, cattle, and goats Bloody or nonbloody The most infamous member of this pathotype is strain O157:H7, which causes bloody diarrhea and no ...
A novel strain of Escherichia coli O104:H4 bacteria caused a serious outbreak of foodborne illness focused in northern Germany in May through June 2011. The illness was characterized by bloody diarrhea , with a high frequency of serious complications, including hemolytic–uremic syndrome (HUS), a condition that requires urgent treatment.
Escherichia coli O157:H7 is a serotype of the bacterial species Escherichia coli and is one of the Shiga-like toxin–producing types of E. coli. It is a cause of disease , typically foodborne illness , through consumption of contaminated and raw food, including raw milk and undercooked ground beef .
Some humans can also be asymptomatic carriers. Once the bacteria colonizes, diarrhea followed by bloody diarrhea , hemorrhagic colitis, typically follows. Other serotypes of STEC also cause disease, inlduding HUS, as occurred with E. coli O104:H4, which triggered a 2011 epidemic of STEC-HUS in Germany .
In Escherichia coli, different classes of DNA-damaging agents can initiate the SOS response, as described above. Taking advantage of an operon fusion placing the lac operon (responsible for producing beta-galactosidase, a protein which degrades lactose) under the control of an SOS-related protein, a simple colorimetric assay for genotoxicity is ...
Since 1993, some strains of E. coli have become resistant to multiple types of fluoroquinolone antibiotics. [citation needed] E. coli was identified as one of the six leading pathogens for deaths associated with resistance in 2019 and that year there were 829,000 deaths globally of people with drug-resistant infection from the pathogen. [26]
[2] [failed verification] The ones that do are collectively known as enterohemorrhagic E. coli (EHEC) and are major causes of foodborne illness. When infecting the large intestine of humans, they often cause gastroenteritis , enterocolitis , and bloody diarrhea (hence the name "enterohemorrhagic") and sometimes cause a severe complication ...