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  2. Ribosomal pause - Wikipedia

    en.wikipedia.org/wiki/Ribosomal_pause

    During this process, translation needs to be stopped in order for ribosome profiling to be performed. This may cause a problem with ribosome profiling because the methods that are used to stop translation in an experiment can impact the outcome, which causes incorrect results.

  3. Translatomics - Wikipedia

    en.wikipedia.org/wiki/Translatomics

    Other methods are polysome profiling, full-length translating mRNA profiling , and translating ribosome affinity purification (TRAP-seq). [4] Unlike the transcriptome , the translatome is a more accurate approximation for estimating the expression level of some genes , since the correlation between the proteome and translatome is higher than ...

  4. Repolarization - Wikipedia

    en.wikipedia.org/wiki/Repolarization

    A labeled diagram of an action potential.As seen above, repolarization takes place just after the peak of the action potential, when K + ions rush out of the cell.. In neuroscience, repolarization refers to the change in membrane potential that returns it to a negative value just after the depolarization phase of an action potential which has changed the membrane potential to a positive value.

  5. Afterhyperpolarization - Wikipedia

    en.wikipedia.org/wiki/Afterhyperpolarization

    Schematic of an electrophysiological recording of an action potential, showing the various phases that occur as the voltage wave passes a point on a cell membrane.The afterhyperpolarisation is one of the processes that contribute to the refractory period.

  6. Translational regulation - Wikipedia

    en.wikipedia.org/wiki/Translational_regulation

    Due to the fact that translation elongation is an irreversible process, there are few known mechanisms of its regulation. However, it has been shown that translational efficiency is reduced via diminished tRNA pools, which are required for the elongation of polypeptides.

  7. Inward-rectifier potassium channel - Wikipedia

    en.wikipedia.org/wiki/Inward-rectifier_potassium...

    K ir channels close upon depolarization, slowing membrane repolarization and helping maintain a more prolonged cardiac action potential. This type of inward-rectifier channel is distinct from delayed rectifier K + channels , which help repolarize nerve and muscle cells after action potentials ; and potassium leak channels , which provide much ...

  8. Comparison of different machine translation approaches

    en.wikipedia.org/wiki/Comparison_of_different...

    A rendition of the Vauquois triangle, illustrating the various approaches to the design of machine translation systems.. The direct, transfer-based machine translation and interlingual machine translation methods of machine translation all belong to RBMT but differ in the depth of analysis of the source language and the extent to which they attempt to reach a language-independent ...

  9. Transcription-translation coupling - Wikipedia

    en.wikipedia.org/wiki/Transcription-translation...

    Translation promotes transcription elongation and regulates transcription termination. Functional coupling between transcription and translation is caused by direct physical interactions between the ribosome and RNA polymerase ("expressome complex"), ribosome-dependent changes to nascent mRNA secondary structure which affect RNA polymerase activity (e.g. "attenuation"), and ribosome-dependent ...