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Phospholipids [1] are a class of lipids whose molecule has a hydrophilic "head" containing a phosphate group and two hydrophobic "tails" derived from fatty acids, joined by an alcohol residue (usually a glycerol molecule). Marine phospholipids typically have omega-3 fatty acids EPA and DHA integrated as part of the phospholipid molecule. [2]
Phospholipids can occur in many biological classes (such as in plant roots, fungi, as well as in soil bacteria), so care has to be taken in over-assigning PLFA biomarkers to the wrong class. Even though phospholipids occur in many different life forms, the fatty acid side chains between differing life forms can be quite unique.
Bottom: 9, lipid bilayer of bacteria and eukaryotes; 10, lipid monolayer of some archaea. Glycerophospholipids or phosphoglycerides are glycerol-based phospholipids. They are the main component of biological membranes in eukaryotic cells. They are a type of lipid, of which its composition affects membrane structure and properties. [1]
Of the phospholipids, the most common headgroup is phosphatidylcholine (PC), accounting for about half the phospholipids in most mammalian cells. [36] PC is a zwitterionic headgroup, as it has a negative charge on the phosphate group and a positive charge on the amine but, because these local charges balance, no net charge.
Plasmalogens are found in multiple domains of life, including mammals, invertebrates, protozoa, and anaerobic bacteria. They are commonly found in cell membranes in the nervous, immune, and cardiovascular systems. [1] [2] [3] In humans, lower levels of plasmalogens are studied in relation to some diseases. Plasmalogens are also associated with ...
The phospholipids of archaea are unusual in four ways: They have membranes composed of glycerol-ether lipids, whereas bacteria and eukaryotes have membranes composed mainly of glycerol-ester lipids. [131] The difference is the type of bond that joins the lipids to the glycerol moiety; the two types are shown in yellow in the figure at the right.
Biosynthesis of various phospholipids (including phosphatidylethanolamine) in bacteria. Phosphatidylethanolamine (PE) is a class of phospholipids found in biological membranes. [1] They are synthesized by the addition of cytidine diphosphate-ethanolamine to diglycerides, releasing cytidine monophosphate.
Cross-sectional view of the structures that can be formed by phospholipids in an aqueous solution. A biological membrane, biomembrane or cell membrane is a selectively permeable membrane that separates the interior of a cell from the external environment or creates intracellular compartments by serving as a boundary between one part of the cell and another.
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