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  2. Atorvastatin - Wikipedia

    en.wikipedia.org/wiki/Atorvastatin

    From 1996 to 2012, under the trade name Lipitor, atorvastatin became the world's best-selling medication of all time, with more than $125 billion in sales over approximately 14.5 years. [116] and $13 billion a year at its peak, [117] Lipitor alone "provided up to a quarter of Pfizer Inc.'s annual revenue for years." [116]

  3. Pill splitting - Wikipedia

    en.wikipedia.org/wiki/Pill_splitting

    A pill-splitter holding a tablet ready to split. Pill-splitting refers to the practice of splitting a tablet or pill to provide a lower dose of the active ingredient, or to obtain multiple smaller doses, either to reduce cost or because the pills available provide a larger dose than required.

  4. Simvastatin - Wikipedia

    en.wikipedia.org/wiki/Simvastatin

    Simvastatin is an effective serum lipid-lowering drug that can decrease low density lipoprotein (LDL) levels by up to 50%. [ citation needed ] Simvastatin had been shown to interact with lipid-lowering transcription factor PPAR-alpha [ 36 ] and that interaction might control the neurotrophic action of the drug.

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