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Chronic hepatitis C is defined as infection with the hepatitis C virus persisting for more than six months based on the presence of its RNA. [18] Chronic infections are typically asymptomatic during the first few decades, [ 18 ] and thus are most commonly discovered following the investigation of elevated liver enzyme levels or during a routine ...
Sofosbuvir/velpatasvir, sold under the brand name Epclusa among others, is a fixed-dose combination medication for the treatment of hepatitis C in adults. [2] [5] [6] [7] It combines sofosbuvir and velpatasvir. [2] [5] [6] It is more than 90% effective for hepatitis C genotypes one through six. [2]
Sofosbuvir is also used with other medications and longer treatment durations, depending on specific circumstances, genotype and cost-effectiveness–based perspective. For example, for the treatment of genotypes 1, 4, 5, and 6 hepatitis C infections, sofosbuvir can be used in combination with the viral NS5A inhibitor ledipasvir. [16]
Hepatitis C is an infection of the liver caused by the hepatitis C virus (HCV). ... Certain medications are recommended more for certain genotypes (and subgenotypes) of hepatitis C than for others ...
[5] [6] It works against all six types of hepatitis C. [4] At twelve weeks following treatment between 81% and 100% of people have no evidence of hepatitis C. [7] It is taken once a day by mouth with food. [4] [5] The most common side effects are headache, diarrhea, and tiredness. [7] [8] In those with a history of hepatitis B, reactivation may ...
For the other, roughly 70 percent of people with hepatitis C, the body’s immune system cannot boot the virus out so easily, and eventually, the infection becomes ongoing, or chronic, lasting for ...
Hepatitis C Sofosbuvir: Hepatitis C [17] nucleoside analogue reverse transcriptase inhibitor: Stavudine: HIV Taribavirin (Viramidine) Hepatitis Syndromes in which Ribavirin is active [18] Telaprevir: Hepatitis C Telbivudine (Tyzeka) Hepatitis B: Tenofovir alafenamide: Hepatitis B: Tenofovir disoproxil: Hepatitis B, HIV [19] Tipranavir: HIV ...
Ledipasvir/sofosbuvir, sold under the trade name Harvoni among others, is a medication used to treat hepatitis C. [8] It is a fixed-dose combination of ledipasvir and sofosbuvir. [8] Cure rates are 94% to 99% in people infected with hepatitis C virus (HCV) genotype 1. [9] Some evidence also supports use in HCV genotype 3 and 4. [9]