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  2. Hypereosinophilic syndrome - Wikipedia

    en.wikipedia.org/wiki/Hypereosinophilic_syndrome

    Depending on eosinophil target-organ infiltration, the clinical presentation of hypereosinophilic syndrome (HES) varies from patient to patient. [13] Individuals with myeloproliferative variant HES may be more likely to experience mucosal ulcerations involving the genitalia or airways, while patients with lymphocytic variant HES typically exhibit prominent skin symptoms such as urticarial ...

  3. Eosinophilia - Wikipedia

    en.wikipedia.org/wiki/Eosinophilia

    The idiopathic hypereosinophilic syndrome is a disorder characterized by hypereosiophilia that is associated with eosinophil-based tissue or organ damage. While almost any organ or tissue may be damaged, the lung, skin, heart, blood vessels, sinuses, kidneys, and brain are the most commonly affected. [ 7 ]

  4. Familial eosinophilia - Wikipedia

    en.wikipedia.org/wiki/Familial_eosinophilia

    Familial eosinophilia is a rare congenital disorder characterized by the presence of sustained elevations in blood eosinophil levels that reach ranges diagnostic of eosinophilia (i.e. 500–1500/microliter) or, far more commonly, hypereosinophilia (i.e. >1,500/microliter).

  5. Clonal hypereosinophilia - Wikipedia

    en.wikipedia.org/wiki/Clonal_hypereosinophilia

    Clonal hypereosinophilia, also termed primary hypereosinophilia or clonal eosinophilia, is a grouping of hematological disorders all of which are characterized by the development and growth of a pre-malignant or malignant population of eosinophils, a type of white blood cell that occupies the bone marrow, blood, and other tissues.

  6. Acute eosinophilic leukemia - Wikipedia

    en.wikipedia.org/wiki/Acute_eosinophilic_leukemia

    It can arise de novo or may develop in patients having the chronic form of a hypereosinophilic syndrome. Patients with acute eosinophilic leukemia have a propensity for developing bronchospasm as well as symptoms of the acute coronary syndrome and/or heart failure due to eosinophilic myocarditis and eosinophil-based endomyocardial fibrosis.

  7. Chronic eosinophilic leukemia - Wikipedia

    en.wikipedia.org/wiki/Chronic_eosinophilic_leukemia

    Signs and symptoms may include weight loss, fever, malaise, cough, skin and mucosal lesions, diarrhea, and peripheral neuropathy.Cardiac symptoms are also possible. [2]In cases associated with PDGFRB and FGFR1 mutations, splenomegaly is common.

  8. Eosinophilic gastroenteritis - Wikipedia

    en.wikipedia.org/wiki/Eosinophilic_gastroenteritis

    Eosinophilic gastroenteritis (EG or EGE), also known as eosinophilic enteritis, [1] is a rare and heterogeneous condition characterized by patchy or diffuse eosinophilic infiltration of gastrointestinal (GI) tissue, first described by Kaijser in 1937.

  9. Eosinophil - Wikipedia

    en.wikipedia.org/wiki/Eosinophil

    imatinib (STI571) – inhibits PDGF-BB in hypereosinophilic leukemia Monoclonal antibodies such as dupilumab and lebrikizumab target IL-13 and its receptor, which reduces eosinophilic inflammation in patients with asthma due to lowering the number of adhesion molecules present for eosinophils to bind to, thereby decreasing inflammation.