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Acetazolamide, sold under the trade name Diamox among others, is a medication used to treat glaucoma, epilepsy, acute mountain sickness, periodic paralysis, idiopathic intracranial hypertension (raised brain pressure of unclear cause), heart failure and to alkalinize urine.
Altitude acclimatization is the process of adjusting to decreasing oxygen levels at higher elevations, in order to avoid altitude sickness. [17] Once above approximately 3,000 metres (10,000 ft) – a pressure of 70 kilopascals (0.69 atm) – most climbers and high-altitude trekkers take the "climb-high, sleep-low" approach.
Acetazolamide is an inhibitor of carbonic anhydrase.It is used for glaucoma, epilepsy (rarely), idiopathic intracranial hypertension, and altitude sickness. For the reduction of intraocular pressure (IOP), acetazolamide inactivates carbonic anhydrase and interferes with the sodium pump, which decreases aqueous humor formation and thus lowers IOP.
Acetazolamide; Altitude sickness; C. Chronic mountain sickness; Climb to Fight Breast Cancer; E. Effects of high altitude on humans; F. Frostbite; H. High-altitude ...
The second day ascends over Dead Woman's pass- the highest point on the trail at 4,200 metres. This is the most dangerous point for altitude sickness, though little time is spent at this elevation and the trail descends again to 3,600 metres. From here, the trail only descends until arriving at Machu Picchu at 2,430 metres.
Physiological and symptomatic changes often vary according to the altitude involved. [6] The Lake Louise Consensus Definition for high-altitude pulmonary edema has set widely used criteria for defining HAPE symptoms. [7] In the presence of a recent gain in altitude, the presence of the following: Symptoms: at least two of: Shortness of breath ...
Machu Picchu [a] is a 15th-century Inca citadel located in the Eastern Cordillera of southern Peru on a mountain ridge at 2,430 meters (7,970 ft). [9] Often referred to as the "Lost City of the Incas", [10] it is the most familiar icon of the Inca Empire.
CMS was first described in 1925 by Carlos Monge Medrano, a Peruvian doctor who specialised in diseases of high altitude. [3] While acute mountain sickness is experienced shortly after ascent to high altitude, chronic mountain sickness may develop only after many years of living at high altitude. In medicine, high altitude is defined as over ...