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A blood smear, peripheral blood smear or blood film is a thin layer of blood smeared on a glass microscope slide and then stained in such a way as to allow the various blood cells to be examined microscopically.
Under the microscope, normal red blood cells (RBCs) appear as small concave discs. Their numbers are reported per high-power field. [96] In highly concentrated urine they may shrivel and develop a spiky shape, which is termed crenation, while in dilute urine they can swell and lose their hemoglobin, creating a faint outline known as a ghost ...
A white blood cell differential is a medical laboratory test that provides information about the types and amounts of white blood cells in a person's blood. The test, which is usually ordered as part of a complete blood count (CBC), measures the amounts of the five normal white blood cell types – neutrophils, lymphocytes, monocytes, eosinophils and basophils – as well as abnormal cell ...
In the past, counting the cells in a patient's blood was performed manually, by viewing a slide prepared with a sample of the patient's blood under a microscope. Today, this process is generally automated by use of an automated analyzer, with only approximately 10-20% of samples now being examined manually.
Manual tests can be used to independently confirm abnormal results. Approximately 10–25% of samples require a manual blood smear review, [5] in which the blood is stained and viewed under a microscope to verify that the analyzer results are
A scanning electron microscope (SEM) image of normal circulating human blood. One can see red blood cells, several knobby white blood cells including lymphocytes, a monocyte, a neutrophil, and many small disc-shaped platelets.
Less commonly, a high white blood cell count could indicate certain blood cancers or bone marrow disorders. The number of leukocytes in the blood is often an indicator of disease, and thus the white blood cell count is an important subset of the complete blood count. The normal white cell count is usually between 4 × 10 9 /L and 1.1 × 10 10 /L.
Reference ranges (reference intervals) for blood tests are sets of values used by a health professional to interpret a set of medical test results from blood samples. Reference ranges for blood tests are studied within the field of clinical chemistry (also known as "clinical biochemistry", "chemical pathology" or "pure blood chemistry"), the ...