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Estrogen dominance is widely discussed by many proponents and on many alternative medicine websites, including: Christiane Northrup , former obstetrics and gynaecology physician, believes that estrogen dominance is linked to "allergies, autoimmune disorders, breast cancer, uterine cancer, infertility, ovarian cysts, and increased blood clotting ...
Perimenopausal Estrogen Replacement Therapy Study (PERT) [11] [12] [13] Postmenopausal Estrogen/Progestin Interventions (PEPI) Stockholm Trial or Stockholm Randomized Trial [14] [15] [10] Women's Estrogen for Stroke Trial (WEST) Women's Estrogen Lipid-Lowering Hormone Atherosclerosis Regression Trial (WELL-HART) Women's Health Initiative ...
Raloxifene is used for the prevention and treatment of postmenopausal osteoporosis and breast cancer prevention in high-risk postmenopausal women with osteoporosis. [5] Preclinical and clinical reports suggest that it is considerably less potent than estrogen for the treatment of osteoporosis.
So, the selective ERβ agitator has more clinical value for neurodegenerative diseases). In post-menopausal women, high levels of testosterone and estrogen higher the risk 2-3 times than lower level situation. Women that are not taking hormone replacement therapy (HRT) have lesser risk of breast cancer because of the insulin level increase. [18]
Breast cancer was increased in women treated with estrogen and a progestin, but not with estrogen and progesterone or estrogen alone. Treatment with unopposed estrogen (i.e., an estrogen alone without a progestogen) is contraindicated if the uterus is still present, due to its proliferative effect on the endometrium. The WHI also found a ...
Changes in levels of estrogen-sensitive proteins after treatment with oral estradiol or oral ethinylestradiol in postmenopausal women. [68] [146] FSH is a pituitary protein and represents general/systemic estrogenic effect, while SHBG and PZP Tooltip pregnancy zone protein are hepatic proteins and represent liver estrogenic effect.
Experts call vaginal estrogen "the holy grail" for its effectiveness in improving vulvar or vaginal itching and burning, painful sex and recurring UTIs.
In the context of the menopause, menopausal hormone therapy (MHT) is the use of estrogen in women without a uterus and estrogen plus progestogen in women who have an intact uterus. [81] MHT may be reasonable for the treatment of menopausal symptoms, such as hot flashes. [82]
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