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Sodium calcium edetate's primary use is to treat lead poisoning, [2] for which it is an alternative to succimer. [3] It is given by slow injection into a vein or into a muscle. [2] For lead encephalopathy sodium calcium edetate is typically used together with dimercaprol. [3] It may also be used to treat plutonium poisoning. [5]
Dimercaprol has long been the mainstay of chelation therapy for lead or arsenic poisoning, [7] and it is an essential drug. [6] It is also used as an antidote to the chemical weapon Lewisite . Nonetheless, because it can have serious adverse effects , researchers have also pursued development of less toxic analogues, [ 7 ] such as succimer .
In the 18th century lead poisoning was fairly frequent on account of the widespread drinking of rum, which was made in stills with a lead component (the "worm"). It was a significant cause of mortality amongst slaves and sailors in the colonial West Indies. [281] [282] Lead poisoning from rum was also noted in Boston. [283]
Mandatory blood testing and a 2004 law requiring lead paint inspections have paid dividends, contributing to a big drop in the number of reported poisoning cases each year. But for children in many of the poorest parts of the city — areas populated overwhelmingly by minorities and immigrants — the risk of lead poisoning remains stubbornly ...
Toxic encephalopathy is a neurologic disorder caused by exposure to neurotoxic organic solvents such as toluene, following exposure to heavy metals such as manganese, as a side effect of melarsoprol treatment for African trypanosomiasis, adverse effects to prescription drugs, or exposure to extreme concentrations of any natural toxin such as cyanotoxins found in shellfish or freshwater ...
Lead Exposure Elimination Project (LEEP) is an international non-governmental organization aimed at reducing lead exposure in low- and middle-income countries. [1] Based in London, England , it was founded in 2020 to promote research and advocacy on the prevalence and consequences of lead poisoning in the developing world. [ 1 ]
Lead poisoning activist Tamara Rubin, aka Lead Safe Mama, first brought attention to the presence of lead in Stanley tumblers in March 2023. Rubin earns a commission on the products she recommends ...
Lead poisoning epidemics refer to specific instances of mass lead poisoning. These events often occur without the knowledge of the communities they affect. Common causes of lead poisoning epidemics include mining, lead recycling, and food/water contamination. [1] These events also cause disproportionate childhood fatalities as children are more ...