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A cold sore [a] is a type of herpes infection caused by the herpes simplex virus that affects primarily the lip. [1] Symptoms typically include a burning pain followed by small blisters or sores . [ 1 ]
In 2009, acyclovir in combination with hydrocortisone cream, marketed as Xerese, was approved in the United States for the early treatment of recurrent herpes labialis (cold sores) to reduce the likelihood of ulcerative cold sores and to shorten the lesion healing time in adults and children (six years of age and older). [61] [62]
Cold sores, also known as fever blisters, can appear on your mouth or lip and are usually caused by oral herpes or herpes simplex virus type 1 (HSV-1). “It’s extremely ubiquitous,” says ...
Because penciclovir is absorbed poorly when given orally (by mouth) it is more often used as a topical treatment. It is the active ingredient in the cold sore medications Denavir (NDC 0135-0315-52), Vectavir and Fenivir. Famciclovir is a prodrug of penciclovir with improved oral bioavailability. Penciclovir was approved for medical use in 1996. [2]
The cold sores they got didn’t last as long and were less severe, too. Many of the most innovative treatments for oral herpes, however, are still in the early stages and being tested on animals.
If the cold sore is painful, icing it can help as can non-prescription gels or ointment with benzocaine, lidocaine, dibucaine, or benzyl alcohol, and/or over-the-counter pain relievers such as ...
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