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Oral glucosamine is a dietary supplement and is not a prescription drug in the United States. [4] [6] Glucosamine is marketed as a supplement to support the structure and function of joints, and the marketing is targeted to people with osteoarthritis. [4] [6]
A significant amount of research has been performed on glycosaminoglycans, especially glucosamine and chondroitin, for the treatment of arthritis.These compounds are commonly marketed as nutritional supplements and numerous 'soft therapeutic claims' are made about their health benefits - especially in aging populations. [1]
It is a secondary amide between glucosamine and acetic acid. It is significant in several biological systems. It is part of a biopolymer in the bacterial cell wall, which is built from alternating units of GlcNAc and N-acetylmuramic acid (MurNAc), cross-linked with oligopeptides at the lactic acid residue of MurNAc.
Chondroitin as a supplement is now commonly used (often in combination with glucosamine) in treating the joint disease of osteoarthritis. [2] In contrast to the symptomatic treatments, chondroitin can modify the progression of a disease process in the patient which it can be used as an alternative medicine. [ 2 ]
On its own, Glucosamine Sulfate is commonly prescribed to treat “inflammation, breakdown, and eventual loss of cartilage (osteoarthritis).” [7] However, the relief is short-term. A double-blind study has recently proven that significant increase in effectivity when Glucosamine Sulfate is used in tandem with Celadrin.
Glucosamine. In organic chemistry, an amino sugar is a sugar molecule in which a hydroxyl group has been replaced with an amine group.More than 60 amino sugars are known, with one of the most abundant being N-acetyl-D-glucosamine (a 2-amino-2-deoxysugar), which is the main component of chitin.
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