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Basophilic is a technical term used by pathologists. It describes the appearance of cells , tissues and cellular structures as seen through the microscope after a histological section has been stained with a basic dye .
The most common such dye is eosin, which stains acidophilic substances red and is the source of the related term eosinophilic. Note that a single cell can have both acidophilic substances/organelles and basophilic substances/organelles, albeit some have historically had so much of one stain that the cell itself is called an eosinophil.
In the anterior pituitary, the term "acidophil" is used to describe two different types of cells which stain well with acidic dyes.. somatotrophs, which secrete growth hormone (a peptide hormone)
An anterior pituitary basophil is a type of cell in the anterior pituitary which manufactures hormones.. It is called a basophil because it is basophilic (readily takes up bases), and typically stains a relatively deep blue or purple.
Main staining types when using hematoxylin and eosin (H&E). A basophil granulocyte is surrounded by lightly staining eosinophilic erythrocytes in an H&E staining. ...
Acidophiles or acidophilic organisms are those that thrive under highly acidic conditions (usually at pH 5.0 or below [1]). These organisms can be found in different branches of the tree of life , including Archaea , Bacteria , [ 2 ] and Eukarya .
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Hematoxylin staining shown as "basophilic" at top, seen with dual staining with hematoxylin and eosin (H&E). Haematoxylin stain is commonly followed (or counterstained) with another histologic stain, eosin. [10] [11] [1] When paired, this staining procedure is known as H&E staining, and is one of the most commonly used combinations in histology.