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Hydralazine, sold under the brand name Apresoline among others, is a medication used to treat high blood pressure and heart failure. [2] This includes high blood pressure in pregnancy and very high blood pressure resulting in symptoms . [ 3 ]
It is a combination of hydralazine hydrochloride (an arteriolar vasodilator) and isosorbide dinitrate (a nitrate vasodilator). [ 1 ] [ 2 ] The US Food and Drug Administration (FDA) approved medication to treat congestive heart failure in specifically self-identified Black patients.
While hydralazine is the most well-known compound in this class, other related drugs such as dihydralazine also belong to the hydrazinophthalazine family and exhibit similar antihypertensive properties. These compounds have been in clinical use since the mid-20th century, with hydralazine being discovered in the 1940s and approved by the FDA in ...
Isosorbide dinitrate is a medication used for heart failure, esophageal spasms, and to treat and prevent chest pain from not enough blood flow to the heart. [1] It has been found to be particularly useful in heart failure due to systolic dysfunction together with hydralazine.
Dihydralazine is a prescription drug [1] with antihypertensive properties. [2] It functions by combating the effects of adrenaline, and by expanding the blood vessels so as to enable smoother flow of blood by decreasing the pressure.
This page was last edited on 11 December 2007, at 10:28 (UTC).; Text is available under the Creative Commons Attribution-ShareAlike 4.0 License; additional terms may apply.
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This page was last edited on 12 January 2025, at 04:23 (UTC).; Text is available under the Creative Commons Attribution-ShareAlike 4.0 License; additional terms may apply.
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