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Lhermitte–Duclos disease (LDD) (English: / ˌ l ɛər ˈ m iː t ˌ d uː ˈ k l oʊ /), also called dysplastic gangliocytoma of the cerebellum (DGC), is a rare, slowly growing tumor of the cerebellum, a gangliocytoma sometimes considered to be a hamartoma, characterized by diffuse hypertrophy of the granular layer of the cerebellum.
Various kinds of tumors, usually primary and benign, are represented in the pathology. Lesions in the area of cerebellopontine angle cause signs and symptoms secondary to compression of nearby cranial nerves , including cranial nerve V (trigeminal), cranial nerve VII (facial), and cranial nerve VIII (vestibulocochlear).
Some symptoms in adults are specific to the location of the tumor: Tumors in the cerebrum, which controls movement, may cause weakness or numbness to the body. This weakness is often limited to one side of the body. Tumors in the Broca's area of the cerebrum can cause speech difficulties. In extreme cases, the patient may have problems ...
A nervous system tumor is a tumor that arises within the nervous system, either the central nervous system (CNS) or the peripheral nervous system (PNS). [1] [2] Nervous system primary tumors include various types of brain tumor and spinal tumors, such as gliomas, and meningiomas (of the CNS), and schwannomas (of the PNS) and can be either benign or malignant.
This is an accepted version of this page This is the latest accepted revision, reviewed on 13 February 2025. Neoplasm in the brain Medical condition Brain tumor Other names Intracranial neoplasm, brain tumour, brain cancer Brain metastasis in the right cerebral hemisphere from lung cancer, shown on magnetic resonance imaging Specialty Neurosurgery, neuro-oncology Symptoms Vary depending on the ...
Hemangioblastomas usually occur in adults, yet tumors may appear in VHL syndrome at much younger ages. Men and women are approximately at the same risk. Although they can occur in any section of the central nervous system, they usually occur in either side of the cerebellum, the brain stem or the spinal cord. [2] [7]
Paraneoplastic cerebellar degeneration (PCD) is a paraneoplastic syndrome associated with a broad variety of tumors including lung cancer, ovarian cancer, breast cancer, Hodgkin’s lymphoma and others. PCD is a rare condition that occurs in less than 1% of cancer patients.
Neurological symptoms are often caused by increased intracranial pressure, [7] with severe cases resulting in coma. [8] The most common neurological symptoms include: New onset headaches: headaches occur in roughly half of brain metastasis patients, especially in those with many tumors. [6]