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Under the UK drug misuse classification system, alprazolam is a Class C drug. [8] [101] In the UK, alprazolam is not available on the National Health Service (NHS) and can only be obtained on a private prescription. [102] In Ireland, alprazolam is a Schedule 4 medicine. [103] In Sweden, alprazolam is a prescription drug in List IV (Schedule 4 ...
Drug Name Common Trade Names [a] Year Approved Typical Oral Dosage Formulations (mg) Approx. Equivalent Oral Dose to 10 mg Diazepam [b] (mg) Peak Onset of Action (hours) Elimination Half-life of Active Metabolite (hours) Primary Therapeutic Use Adinazolam: Deracyn: Research chemical: 1–2: 3: anxiolytic, antidepressant: Alprazolam
A prescription is needed for possession of all benzodiazepines. Temazepam formulations containing 20 mg or greater of the drug are placed on List 1, thus requiring doctors to write prescriptions in the List 1 format. [219] In East Asia and Southeast Asia, temazepam and nimetazepam are often heavily controlled and restricted.
Benzodiazepine withdrawal syndrome (BZD withdrawal) is the cluster of signs and symptoms that may emerge when a person who has been taking benzodiazepines as prescribed develops a physical dependence on them and then reduces the dose or stops taking them without a safe taper schedule.
*Not all trade names are listed. Click on the drug name to see a more comprehensive list. **The duration of apparent action is usually considerably less than the half-life. With most benzodiazepines, noticeable effects usually wear off within a few hours. Nevertheless, as long as the drug is present it will exert subtle effects within the body.
Pharmacy information systems are a potential source of valuable information for pharmaceutical companies as it contains information about the prescriber's prescribing habits. Prescription data mining of such data is a developing, specialized field. [55] Many prescribers lack the digitized information systems that reduce prescribing errors. [56]
A study found that of 42 patients treated with alprazolam, up to a third of long-term users of the benzodiazepine drug alprazolam develop depression. [40] Studies have shown that long-term use of benzodiazepines and the benzodiazepine receptor agonist nonbenzodiazepine Z drugs are associated with causing depression as well as a markedly raised ...