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Hypertrophic scar. Silicone gel sheeting is the gold-standard and non-invasive treatment for hypertrophic and keloid scars. During skin injury repair, dermal cells proliferate and migrate from the skin tissue to the wound, producing collagen and causing contraction of the placement dermis. [5]
Silicone gel sheeting is sometimes used to treat hypertrophic scars. Silicone gel sheets may improve the appearance of scars slightly compared with applying onion extract, and may reduce pain compared with no treatment with silicone gel sheets or pressure garments. [8]
Keloid, also known as keloid disorder and keloidal scar, [1] ... Topical silicone gel sheeting was introduced as a treatment in the early 1980s. [25] References
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Silicone scar treatments are commonly used in preventing scar formation and improving existing scar appearance. [50] A meta-study by the Cochrane collaboration found weak evidence that silicone gel sheeting helps prevent scarring. [51] However, the studies examining it were of poor quality and susceptible to bias. [51]
By Steven Brill Letter From the Editors Backstage at Johnson & Johnson. On May 20, about 100 stock analysts gathered in the ballroom of the Hyatt Regency Hotel in New Brunswick, New Jersey, to hear good news from top executives at Johnson & Johnson: The company had 10 new drugs in the pipeline that might achieve more than a billion dollars in annual sales.
Artificial skin made by Integra composed of an outer silicone film and inner matrix of cross linked fibers. Artificial skin is a collagen scaffold that induces regeneration of skin in mammals such as humans. The term was used in the late 1970s and early 1980s to describe a new treatment for massive burns.
Silicone rubber applications such as catheters are widespread in medicine, but have several limitations. For example, they exhibit poor tear strength and poor resistance to fatigue . Brittle fracture can occur from defects within sections owing to poor control of vulcanization . [ 2 ]
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