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CA-125 was initially detected using the murine monoclonal antibody designated OC125. Robert Bast , Robert Knapp and their research team first isolated this monoclonal antibody in 1981. [ 28 ] The protein was named "cancer antigen 125" because OC125 was the 125th antibody produced against the ovarian cancer cell line that was being studied.
In November 1868, a fire destroyed the asylum, killing six patients and displacing over 300 others. [5] The hospital was rebuilt in the Kirkbride style in 1877. [ 1 ] The hospital was closed in the late 1980s, and was listed on the National Register of Historic Places in an attempt to save the building in 1986.
Roughly bounded by Parsons Ave., Broad and Main Sts., and the railroad tracks; also 43-125 Parsons Ave., including 684 Oak St. and 690 Franklin Ave. 39°57′43″N 82°57′53″W / 39.961944°N 82.964722°W / 39.961944; -82.964722 ( Columbus Near East Side
40 [15] U/mL: Pancreatic cancer CA-125: 30, [71] 35 [72] ... adult male: 30 85: ng/dL Testosterone: ... Higher in pregnant women [172] 0.5 [5]
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The one biomarker that has been in use over the last 20 years is CA-125. [121] A 2016 review found that this biomarker was present in those with symptoms of endometriosis; and, once ovarian cancer has been ruled out, a positive CA-125 may confirm the diagnosis. [122] Its performance in ruling out endometriosis is low. [122]
Prostate cancer is the most diagnosed cancer in men in over half of the world's countries, and the leading cause of cancer death in men in around a quarter of countries. [ 91 ] Prostate cancer is rare in those under 40 years old, [ 92 ] and most cases occur in those over 60 years, [ 2 ] with the average person diagnosed at 67. [ 93 ]
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