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2. Hematopoietic stem cell transplantation - Wikipedia

   en.wikipedia.org/wiki/Hematopoietic_stem_cell...

   The first physician to perform a successful human bone-marrow transplant on a disease other than cancer was Robert A. Good at the University of Minnesota in 1968. [75] In 1975, John Kersey, also of the University of Minnesota, performed the first successful bone-marrow transplant to cure lymphoma.

3. High-dose chemotherapy and bone marrow transplant - Wikipedia

   en.wikipedia.org/wiki/High-dose_chemotherapy_and...

   The idea for high-dose chemotherapy (HDC) with autologous bone marrow transplant (ABMT) originated in the 1950s as a leukemia treatment, when E. Donnall Thomas had shown that bone marrow could be harvested from a person and transplanted into the same or another person. [2] It was promoted as a treatment for advanced breast cancer starting in ...

4. Multiple myeloma - Wikipedia

   en.wikipedia.org/wiki/Multiple_myeloma

   Five-year survival rate 54% ... some patients undergo a bone marrow transplant ... Multiple myeloma is the second-most prevalent blood cancer (10%) after non ...

5. Graft-versus-host disease - Wikipedia

   en.wikipedia.org/wiki/Graft-versus-host_disease

   In addition, as bone marrow transplantation is frequently used to treat cancer, mainly leukemias, donor T-cells have proven to have a valuable graft-versus-tumor effect. [24] A great deal of current research on allogeneic bone marrow transplantation involves attempts to separate the undesirable graft-vs-host disease aspects of T-cell physiology ...

6. Stem-cell therapy - Wikipedia

   en.wikipedia.org/wiki/Stem-cell_therapy

   Some preliminary clinical trials achieved only modest improvements in heart function following the use of bone marrow stem cell therapy. [52] [53] Stem-cell therapy for the treatment of myocardial infarction usually makes use of autologous bone marrow stem cells, but other types of adult stem cells may be used, such as adipose-derived stem ...

7. Cancer survival rates - Wikipedia

   en.wikipedia.org/wiki/Cancer_survival_rates

   Brain and pancreatic cancers have much lower median survival rates which have not improved as dramatically over the last forty years. [4] Indeed, pancreatic cancer has one of the worst survival rates of all cancers. Small cell lung cancer has a five-year survival rate of 4% according to Cancer Centers of America's Website. [5]

8. Acute lymphoblastic leukemia - Wikipedia

   en.wikipedia.org/wiki/Acute_lymphoblastic_leukemia

   Blood tests and bone marrow examination [3] Differential diagnosis: Infectious mononucleosis, acute myeloid leukemia, lymphoblastic lymphoma, aplastic anemia [3] Treatment: Chemotherapy, stem cell transplantation, radiation therapy, targeted therapy [7] [1] Prognosis: Children: 90% five-year survival rate [2] Adults: 35% five-year survival [8 ...

9. Tumors of the hematopoietic and lymphoid tissues - Wikipedia

   en.wikipedia.org/wiki/Tumors_of_the...

   The more aggressive forms of disease require treatment with chemotherapy, radiotherapy, immunotherapy and—in some cases—a bone marrow transplant. The use of rituximab has been established for the treatment of B-cell–derived hematologic malignancies, including follicular lymphoma (FL) and diffuse large B-cell lymphoma (DLBCL). [7]